Long-term cognitive outcomes in children with CSWS

This study reviewed the long-term neuropsychological outcomes of 25 children diagnosed with CSWS (the old term for the syndrome) and followed them for an average of 13.5 years. The researchers examined how cognitive abilities changed during and after the CSWS phase, and whether factors such as disease duration, treatment response, or underlying neurological conditions influenced long-term outcomes.

The findings showed that cognitive performance worsened during the CSWS phase in nearly all children. Long-term outcomes were highly variable. Some children experienced relatively positive outcomes, particularly those without underlying brain abnormalities, while others had persistent cognitive difficulties. Longer duration of CSWS was associated with poorer outcomes, and overall, 44 percent of children had lasting cognitive impairment.

The study highlights the significant impact CSWS can have on developmental trajectories and reinforces the importance of early recognition and effective treatment to limit the duration of abnormal sleep activity.

Read the full article here:
https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.12313